28 September 2022
The placenta plays a crucial role in human development by supplying the foetus with oxygen and glucose whilst removing waste products. However, when signalling from the placenta goes awry, mothers are at risk of developing an inflammatory condition called preeclampsia. Monika Horvat Merčnik, a student on the international PhD programme ‘Inflammatory disorders in pregnancy’ (DP-iDP), used a Travelling Fellowship from Journal of Cell Science to explore the interactions between placental endothelial cells and resident macrophages in this condition.
19 August 2022
The risk of developing a subtype of leukaemia known as iAMP21-ALL is amplified in individuals that carry the translocated chromosome rob(15;21)c. Connor Gilkes-Imeson used a Travelling Fellowship from Journal of Cell Science to learn 3D correlative light electron microscopy (3D-CLEM), a technique that he plans to apply in his studies of the kinetochore attachments that form at this mutated chromosome.
2 August 2022
Understanding the structural biology underpinning disease can be crucial for informing drug or vaccine design. For example, structural biology can help researchers understand the mechanism that allows a viral spike protein to bind receptors in our cells. However, structural biology research in Africa is suffering from a lack of resources and, consequently, from the loss of skilled researchers who are moving to pursue a career in this field overseas. To address this, BioStruct-Africa ran a workshop that brought the African structural biology community together by providing training and networking opportunities. BioStruct-Africa was awarded one of our Scientific Meeting Grants to support the event.
25 May 2022
Beaks are an important asset for birds that live in environments with limited freshwater. This is because their bills are thought to offer a route for non-evaporative heat loss, helping the birds to regulate their body temperatures without losing water. Mackenzie Roeder, a PhD student from the University of Maine, used a Travelling Fellowship from Journal of Experimental Biology to support her quantification of this effect in the field.
8 April 2022
Ageing is associated with the accumulation of epigenetic changes to a cell’s DNA. Attempts to slow or even reverse ageing understandably attract a lot of attention, and one novel strategy of particular interest is attempting to ‘rejuvenate’ existing cells. With the help of a Travelling Fellowship, PhD student Priscila Chiavellini was able to visit Stanford University to investigate this approach.
26 September 2022
Romania’s Pike Lake is an important refuge for the wide variety of migratory birds that pass through it each year. This summer, it also played host to a community of neuroscientists who had gathered for the tenth edition of the Transylvanian Experimental Neuroscience Summer School (TENSS). Running from 1-21 June 2022, the course was partly funded by one of our Scientific Meeting Grants. …
18 August 2022
Rising sea temperatures are having a devastating effect on tropical corals and, sadly, we have become used to seeing images of bleached and dying reefs on the news. However, the impacts on their Mediterranean counterparts have not received as much attention. A Travelling Fellowship helped fund PhD student Anthony Bonacolta’s trip across the Atlantic to Barcelona, where he was able to lay the foundations for the development of a Mediterranean coral cell atlas.
21 June 2022
2021 Materials, Mimics and Microfluidics: Engineering Tools in Mechanobiology
Assistant Professor Andrew Holle submitted the first Sustainable Conferencing Grant application for 2021. The 3M2021 was a satellite-based hybrid meeting targeted towards Asian-Pacific researchers. …
11 April 2022
Microtubules are hollow rods that form an important part of the cell cytoskeleton. They are built from polymers of tubulin, a protein that can be modified by the removal (or later re-addition) of an amino acid called tyrosine. Tyrosine modification can affect how the microtubules interact with kinesins, which walk along the microtubules and carry cargo from one part of the cell to another. Proper kinesin function is particularly important in neurons, since these cells can reach remarkable lengths and so transporting cargo from one end to another is a significant undertaking.
2 March 2022
Dr Mereena Ushakumary is a postdoctoral researcher studying late lung development in Dr Anne-Karina Perl’s laboratory at Cincinnati Children’s Hospital. With in-person conferences returning after the disruption of the pandemic, she took the opportunity to attend her first Gordon Research Conference.
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