30 September 2022

Peter Rigby is Professor Emeritus of Developmental Biology at the Institute of Cancer Research (ICR), London, an organisation that he led from 1999 to 2011. Peter began his career as a biochemist, and completed his PhD with Brian Hartley in Cambridge, where he studied enzyme evolution. He then moved to Stanford to work with Paul Berg, focusing his postdoctoral research on SV40, a virus that can transform its host into a tumour cell. “It was clear to myself and my peers that it was time to stop working on E. coli and to start working on eukaryotic cells,” Peter said, “and the only way to get inside the workings of a eukaryotic cell was by using viruses.”

26 September 2022

Romania’s Pike Lake is an important refuge for the wide variety of migratory birds that pass through it each year. This summer, it also played host to a community of neuroscientists who had gathered for the tenth edition of the Transylvanian Experimental Neuroscience Summer School (TENSS). Running from 1-21 June 2022, the course was partly funded by one of our Scientific Meeting Grants.

19 August 2022

The risk of developing a subtype of leukaemia known as iAMP21-ALL is amplified in individuals that carry the translocated chromosome rob(15;21)c. Connor Gilkes-Imeson used a Travelling Fellowship from Journal of Cell Science to learn 3D correlative light electron microscopy (3D-CLEM), a technique that he plans to apply in his studies of the kinetochore attachments that form at this mutated chromosome.

10 August 2022

Steve Royle is based at the Centre for Mechanochemical Cell Biology, Warwick Medical School, where his team is investigating the molecular mechanisms that underpin two important cellular processes: membrane trafficking and mitosis. “We’re interested in the nuts and bolts of how these key processes work,” Steve explained.

2 August 2022

Understanding the structural biology underpinning disease can be crucial for informing drug or vaccine design. For example, structural biology can help researchers understand the mechanism that allows a viral spike protein to bind receptors in our cells. However, structural biology research in Africa is suffering from a lack of resources and, consequently, from the loss of skilled researchers who are moving to pursue a career in this field overseas. To address this, BioStruct-Africa ran a workshop that brought the African structural biology community together by providing training and networking opportunities. BioStruct-Africa was awarded one of our Scientific Meeting Grants to support the event.

28 September 2022

The placenta plays a crucial role in human development by supplying the foetus with oxygen and glucose whilst removing waste products. However, when signalling from the placenta goes awry, mothers are at risk of developing an inflammatory condition called preeclampsia. Monika Horvat Merčnik, a student on the international PhD programme ‘Inflammatory disorders in pregnancy’ (DP-iDP), used a Travelling Fellowship from Journal of Cell Science to explore the interactions between placental endothelial cells and resident macrophages in this condition.

22 August 2022

Sally Lowell is a developmental and stem cell biologist at the University of Edinburgh, UK. “My group is interested in how cells build embryos and tissues, and how we can control the behaviour of these cells in culture,” she explained. She is particularly interested in the local ‘conversations’ that cells have when communicating with their neighbours, and how these local interactions can affect their fate within the developing embryo. Sally’s lab is developing tools to ‘listen in’ on the communications between cells. They are also investigating how differences in cell adhesion and tissue morphology can affect this communication.

18 August 2022

Rising sea temperatures are having a devastating effect on tropical corals and, sadly, we have become used to seeing images of bleached and dying reefs on the news. However, the impacts on their Mediterranean counterparts have not received as much attention. A Travelling Fellowship helped fund PhD student Anthony Bonacolta’s trip across the Atlantic to Barcelona, where he was able to lay the foundations for the development of a Mediterranean coral cell atlas.

8 August 2022

We rounded off June with a slightly unusual Workshop, which aimed to nurture new voices in science writing. Organised by Buzz Baum, Enrico Coen, Mark Miodownik and Jennifer Rohn, the Workshop brought aspiring writers, established authors and agents together in the beautiful surroundings of Wiston House, Sussex.

29 July 2022

Holly Shiels is based at the University of Manchester, UK, where her lab investigates the interplay between environment and cardiac physiology. They are currently working on the tolerance of fishes to hypoxia and to changes in temperature, as well as the effects of microplastics and crude oil on cardiac health. This latter research area also relates to broader concerns about air pollution, since crude oil contains polyaromatic hydrocarbons, which are the same molecules that form a ‘corona’ around particulate matter in the air we breathe.