16 May 2023
Neurodevelopmental disorders (NDDs) represent a growing challenge in modern medicine and may give rise to impaired cognition, communication, and psychomotor skills. It is therefore very important that more sophisticated in vitro models are created to reveal the complexities of these disorders.
3 March 2023
The transmembrane potential (Vmem) is the difference in electrical potential across a cell membrane, acute changes in Vmem can result in multiple differences in cellular signalling pathways and cell processes such as differentiation, proliferation and cell:cell communication.
8 March 2023
The 14-3-3 protein family comprises a group of scaffold proteins implicated in metabolic processes. Using a Travelling Fellowship from Journal of Cell Science, Samanta Del Veliz visited Gareth Lim’s lab to investigate the role of these proteins in mesenchymal stem cell differentiation.
16 January 2023
Microphysiological systems (MPS), including organoids and organs-on-a-chip, have received growing attention in recent years. The first meeting in India to focus on this topic was held from 31 October – 4 November 2022, and was part of the India-EMBO Lecture Course series. The Company of Biologists was delighted to help support the meeting with funding that contributed to student accommodation waivers. The meeting brought together students and experts from across India and around the world, and included hands-on sessions to help participants really get to grips with MPS research.
26 September 2022
Romania’s Pike Lake is an important refuge for the wide variety of migratory birds that pass through it each year. This summer, it also played host to a community of neuroscientists who had gathered for the tenth edition of the Transylvanian Experimental Neuroscience Summer School (TENSS). Running from 1-21 June 2022, the course was partly funded by one of our Scientific Meeting Grants. …
25 April 2023
Multiple sclerosis (MS) is a central nervous system demyelinating disease with heterogeneous clinical manifestations. Most MS patients start with reversible neurological deficits, which is the relapsing-remitting MS (RRMS) subtype that could be controlled by disease-modifying therapies and anti-CD20 therapeutics.
3 March 2023
The teeth of killer whales grow in layers, layers that can be analysed to reveal the diet of an individual animal, over the course of a specific time frame. Material from inside the teeth cavity, known as dentine, can be extracted and stable isotope analysis used to investigate ecological behaviours such as large-scale movements. Maeva Terrapon, a student from the University of St Andrews used a Travelling Fellowship from Journal of Experimental Biology, to investigate the ecology of killer whales alongside fellow researchers at the Department of Fisheries and Oceans (DFO), Winnipeg, Canada. …
1 February 2023
With the help of a DMM Conference Travel Grant, Jazib Shafiq was recently able to travel from Pakistan to attend the EMBO practical course on metabolite and species dynamics in microbial communities.
28 September 2022
The placenta plays a crucial role in human development by supplying the foetus with oxygen and glucose whilst removing waste products. However, when signalling from the placenta goes awry, mothers are at risk of developing an inflammatory condition called preeclampsia. Monika Horvat Merčnik, a student on the international PhD programme ‘Inflammatory disorders in pregnancy’ (DP-iDP), used a Travelling Fellowship from Journal of Cell Science to explore the interactions between placental endothelial cells and resident macrophages in this condition.
19 August 2022
The risk of developing a subtype of leukaemia known as iAMP21-ALL is amplified in individuals that carry the translocated chromosome rob(15;21)c. Connor Gilkes-Imeson used a Travelling Fellowship from Journal of Cell Science to learn 3D correlative light electron microscopy (3D-CLEM), a technique that he plans to apply in his studies of the kinetochore attachments that form at this mutated chromosome.
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