Developmental Metabolism and the Origins of Health and Disease
Organisers: Sally Dunwoodie and Alex Gould
Metabolism is central to the functions of all cells and its importance in the field of cancer has been clear for many years. Much more recently, developmental biologists have begun to appreciate how metabolism intersects with the processes of growth, patterning and differentiation. The developmental origins of health and disease (DOHaD) is one clinically relevant field of developmental biology where many of the mechanistic links between early-life environmental factors, such as nutrition, and adult physiology remain unclear. Recent advances in developmental metabolism and sophisticated new metabolomics techniques now offer a promising route towards identifying these missing links.
This Workshop brings together a multidisciplinary group of developmental biologists, experts in nutrition and metabolism, and researchers interested in DOHaD. The invited speakers include clinical researchers as well as scientists covering a range of invertebrate and vertebrate models.
The program includes presentations and discussions on four intersecting themes:
- Nutrition and metabolism
- Metabolism of development
- Developmental origins of health and disease
- Metabolism in disease
The Workshop provides a small, friendly and focused setting in which to develop new ideas bridging these four themes. Our goal is to inspire new cross-disciplinary research directions aimed at discovering the mechanistic links between early-life metabolism and adult disease.
Organisers & speakers
Sally Dunwoodie, Victor Chang, Australia
Alex Gould, Francis Crick Institute, UK
Jens Brüning, Max Planck Institute, Cologne, Germany
Ralph Deberardinis, UT Southwestern, USA
Lydia Finley, Memorial Sloan Kettering Cancer Center, New York,USA
Dino Giussani, University of Cambridge, UK
Keith Godfrey, University of Southampton, UK
Myriam Hemberger, University of Calgary, Canada
Pierre Leopold, Institute Curie, Paris, France
Susan Ozanne, Metabolic Research Laboratories, Cambridge, UK
Willhelm Palm, German Cancer Research Center (DKFZ), Heidelberg, Germany
Linda Partridge, University College London, London, UK
Norbert Perrimon, Harvard Medical School, HHMI, USA
Olivier Pourquie, Harvard Stem Cell Institute, USA
Theresa Powell, University of Colorado, USA
Tristan Rodriguez, Imperial College, London, UK
Aurelio Teleman, German Cancer Research Center (DKFZ), Heidelberg, Germany
Marian Walhout, UMass, Worcester, USA
Applications are currently closed. We will be reopening applications once a rescheduled date has been finalised.
We offer 12 funded places for early-career researchers to attend this Workshop along with the 18 invited speakers. We just ask that you pay for your own travel costs. If you would like to attend please complete the application form and attach a one page CV and a letter of support from your supervisor. If your supervisor would prefer to send the letter directly to us please ask them to email it to email@example.com
All attendees are expected to actively contribute to the Workshops by asking questions at presentation sessions and taking part in discussions, as well as giving a short talk on their research.
At some Workshops, early-career researchers are given additional responsibilities to promote their involvement, such as:
- Write a daily blog for the Node
- Summarise the previous day’s themes to set the scene for the next day’s sessions
- Propose future directions and collaborations
- Make a short 2 minute video on their experience at the Workshop
Most of these activities would be carried out in pairs or small groups and often with the
support of more senior scientists present.