The DNA in our cells is subject to daily damage from metabolic agents and environmental factors, but most of this damage is successfully repaired by natural systems throughout the cell cycle. However, accumulation of DNA damage due to failures in these natural repair systems is an important risk factor in cancer development. …
Intranasal insulin has been shown to improve memory in both humans and mice. However, in most cases less than 0.05% of insulin delivered via the intranasal route actually reaches the brain. Buccal epithelium is routinely used as an in vitro model for investigating peptide uptake, but Elizabeth Rhea, a postdoctoral fellow in the Department of Medicine at the University of Washington, USA, wished to investigate its potential as a model for screening enhancers of intranasal insulin delivery. …
As a new assistant professor at James Cook University (JCU), marine conservation physiologist Jodie Rummer applied to the Journal of Experimental Biology for a Travelling Fellowship to perform fieldwork at Lizard Island Research Station in the Northern Great Barrier Reef of Australia. …
Getting involved as an organiser for one of our Workshops is easy. We focus on the logistics, so you can focus solely on the science. Are you thinking about proposing a topic for one of our Workshops? Watch this video to hear from some of our previous organisers.
One of the research areas of the Martinez-Arias lab in the Department of Genetics at the University of Cambridge, UK, is the development of gastruloids – small, self-organising aggregates of mouse embryonic stem cells. PhD student Peter Baillie-Johnson was working on the generation of elongating gastruloids to mimic the first stages of axial elongation in the mouse embryo, but was limited by aggregates adhering to the surface of culture plates. …
The research project of PhD student Filomena Caccavale at the Stazione Zoologica Anton Dohrn in Naples, Italy, has focussed on the role of nitric oxide (NO) during embryonic and larval development of the cephalochordate Branchiostoma lanceolatum (amphioxus). …
In the autumn of 2017 I undertook my PIPs internship at The Company of Biologists, the publisher behind five major journals including Development – the journal which hosts the community site the Node. I was keen to experience the publishing side of science, and see what a non-academic career in science could be like.
Aidan Maartens (the Node Community Manager) and Sarah Morson (intern).
I carried out my PIPS placement at The Company of Biologists – a decision largely driven by my interest in gaining insight into the publishing process in preparation for submitting my own articles, and also to find out more about publishing as an alternative career path after my PhD.
Katherine Brown (Development), Caitlin McQueen (intern), Rachel Hackett (Disease Models & Mechanisms and Biology Open) and Sharon Ahmad (Journal of Cell Science).
Early-career researchers can apply for a funded place at one of our Workshops. This is a great opportunity that could enhance your career in various ways. Watch the video to hear from some of our previous attendees on why they applied and how it has benefited them.
The bacterial cytoskeleton controls many important cellular processes including bacterial cell morphogenesis, division and motility. Elements of the bacterial cytoskeleton mirror the major components of the cytoskeleton in eukaryotic cells; for example, the actin homologue MreB, the tubulin homologue FtsZ and the intermediate filament homologue CreS. …
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