Symbiosis in the microbial world: from ecology to genome evolution
Organisers: Laura Eme, F. Joseph Pollock, Jean-Baptiste Raina, Anja Spang, Tom Williams and John Archibald
Date: 5 - 9 November 2017
Location: Wiston House, UK
Symbiosis – intimate and persistent interaction between two or more distinct biological entities – has historically received less attention than other interactions such as predation or competition, but is increasingly recognized as one of the key selective forces in evolution. Most species from across the tree of life have been shaped by a long history of interdependent co-evolution, from the bacterial endosymbionts that provide insects with vital nutrients to the mitochondria that power our own cells. This Workshop will address the origin, maintenance, and long-term implications of symbiosis among microbes from the complementary perspectives of cell biology, ecology, evolution and genomics in both model and non-model organisms.
The key topics will include:
- Steps on the road towards microbial symbiosis
- Evolution and maintenance of symbiosis
- Marine symbioses
- Symbiosis and organismality
Motivations, aims and anticipated outcomes:
In recent years, symbiosis has gained recognition as one of the most important evolutionary processes shaping biodiversity throughout the history of life on Earth. Symbiosis ranges from metabolic and defensive interactions among free-living microbes through cellular and genomic integration to the origins of mitochondria and chloroplasts. As such, it provides an unparalleled route to evolutionary innovation that has driven many of the key transitions in the history of life.
Now is the ideal time for a multidisciplinary meeting on symbiosis research, which is currently experiencing unprecedented progress due to a wide range of recent methodological breakthroughs. Next-generation sequencing, including techniques for reconstructing genomes from single cells or environmental samples, has greatly improved our sampling of natural symbiotic diversity and our understanding of interactions among and between microbes in the wild. This flood of new data has been complemented by proteomics and new experimental techniques such as nano-SIMS technologies (which enable intra-cellular measurement of molecular and metabolic flux), and transfection systems for the genetic manipulation of a wider range of organisms. Collectively, these developments have opened up entirely new lines of research for biologists interested in symbiosis, for the first time bringing both classical and emerging questions into the realm of tractable science.
This growth of activity, as well as the fundamental importance of the topic to many areas of biology, is reflected by the rapidly expanding literature on the subject (over 1,000 publications in 2014 alone) including a series of recent, high profile publications by our organisers and participants (see below).
Current research is proceeding on multiple fronts – from microbial ecologists studying the interactions among present-day prokaryotic consortia to cell biologists and evolutionists who are investigating the long-term impacts of symbiosis on cellular integration and genome evolution. In fact, the breadth of approaches and perspectives could be a key strength in this field of research if communication was improved between researchers that are approaching these questions from different angles.
The aim of our proposal is to unite leaders and promising early career researchers from each of these disciplines with the overarching objective to forge a much-needed synthesis on the cellular, ecological, evolutionary and even theoretical/philosophical aspects of symbiosis and its role and importance in the evolution of life on Earth. This synthesis will aim to highlight points of consensus and underlying connections between these different fields, but also to identify aspects where future efforts of multidisciplinary work should best be focused on.
Our overall goal is not only to stimulate fruitful discussions, future collaborations, and to establish an integrative framework for research in all these fields but also to identify the most important contemporary questions in the field of symbiotic research, which can only be tackled by the combination of different tools, approaches and expertise.
Organisers & speakers
F Joseph Pollock Pennsylvania State University, USA
Jean-Baptiste Raina University of Technology Sydney, Australia
Anja Spang Royal Netherlands Institute for Sea Research, The Netherlands
Tom Williams Bristol University, UK
John Archibald Dalhousie University, UK
Thomas Bosch University of Kiel, Germany
Michael Brockhurst University of Sheffield, UK
Andreas Brune Max Plank Institute, Germany
Cindy Castelle University of California, Berkeley, USA
Angela Douglas Cornell University, USA
Nicole Dubilier Max Planck Institute, Germany
Genoveva Esteban Bournemouth University, UK
Diego Gonzalez University of Lausanne, Switzerland
Yoshihisa Hirakawa University of Tsukuba, Japan
Anna Karnkowska University of Warsaw, Poland
Nick Lane University College London, UK
Margaret McFall-Ngai University of Hawaii at Manoa, USA
Mónica Medina Pennsylvania State University, USA
Nancy Moran University of Texas at Austin, USA
Joel Sachs University of California, Riverside, USA
Roman Stocker ETH Zurich, Switzerland
Ross Waller University of Cambridge, UK
Nicole Webster Australian Institute of Marine Science, Australia
Early career scientists
We offer around 10 funded places for early career scientists to attend our Workshops along with the 20 speakers. We just ask that you pay for your own travel costs. If you would like to attend please complete the application form and attach a one page CV and a letter of support from your supervisor.
All attendees are expected to actively contribute to the Workshops by asking questions at presentation sessions and taking part in discussions.
At some Workshops, early career scientists are given additional responsibilities to promote their involvement, such as:
- Write a daily blog for the Node
- Summarise the previous day’s themes to set the scene for the next day’s sessions
- Present a poster on their research interests
- Propose future directions and collaborations
- Give a short talk on their research
- Make a short 2 minute video on their experience at the
Most of these activities would be carried out in pairs or small
groups and often with the support of more senior scientists
About Wiston House
The Workshops will be held at the beautiful Wiston House, which is a 16th century Grade I listed building located at the foot of the South Downs in West Sussex. The house is surrounded by over 6,000 acres of parkland with magnificent views from the mile-long drive.
Wiston House is the home of Wilton Park, one of the world’s leading centres for the discussion of key international policy issues. Wilton Park was created in 1946 to help re-establish peace and democracy in Europe as part of an initiative inspired by Winston Churchill. Wiston House has an amazing history and appears in the Domesday Book, the register of English possessions made by William the Conqueror in 1086, 20 years after he won the Battle of Hastings.
Wiston House is 32 miles from Gatwick Airport and 60 miles from Heathrow Airport. The nearest train station is Shoreham-by-Sea, which is a 20 minute taxi ride from Wiston House and takes 1 hour 10 minutes from London Victoria.
Tel: +44 (0) 1903 815020