Collective Cell Migration: From In Vitro to In Vivo

Organisers: David Bryant, Nir Gov, Laura Machesky and Denise Montell

Date: 19-22 February 2023

Location: Buxted Park, East Sussex, UK

Collective cell migration has paramount importance for embryogenesis, tissue repair and cancer progression. This phenomenon spans from the microscopic, molecular scale of cell signalling and cell-cell interactions, to the macroscopic, tissue-level scale of multicellular dynamics, and is amenable to both experimental and theoretical investigations. Collective cell migration is distinctly different from single cell migration in terms of its biological complexity and theoretical treatment.

Our interdisciplinary program focuses on four key topics of collective cell migration, ranging from the molecular to the organismal level:

  1. Cellular mechanisms of collective movement and metastasis
  2. Mechanobiology of morphogenesis
  3. Biophysical and mathematical modelling of collective movement and morphogenesis
  4. In vivo imaging of migration and metastasis

This allows us to bring together a diverse and dynamic range of speakers, spanning the cell biology, developmental biology, physics, mathematics, and in vivo imaging fields. We believe that this multidisciplinary approach will not only facilitate interactions between alternate approaches and viewpoints but will engender an atmosphere of thinking outside one’s discipline. This Workshop aims to bring together these complementary fields to reach a common consensus on the challenges in our understanding of how cells collectively move, and how this collective migration contributes to metastasis.

About Buxted Park

The Workshop will be held at the beautiful Buxted Park in East Sussex which dates back to the 12th century. The current house was built in 1722 by Sir Thomas Medley and is an elegant Grade II Palladian mansion set in 312 acres of parkland. Over the years it has played host to a number of high profile visitors including William Wordsworth, Winston Churchill, and George V and Queen Mary. Whilst it was a health hydro in the 1960s Gregory Peck, Dudley Moore and Marlon Brando were regular visitors.

Buxted Park is less than 25 miles from Gatwick Airport and 60 miles from Heathrow Airport. There are direct trains taking 1 hour 10 minutes from London Bridge to the village of Buxted which is only a mile away from the hotel.

Buxted Park Hotel
Station Road
East Sussex
TN22 4AY
Tel: +44 (0) 1825 733333


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