Collective Cell Migration: From In Vitro to In Vivo

Organisers: David Bryant, Nir Gov, Laura Machesky and Denise Montell

Date: 19-22 February 2023

Location: Wiston House, West Sussex, UK

Collective cell migration has paramount importance for embryogenesis, tissue repair and cancer progression. This phenomenon spans from the microscopic, molecular scale of cell signalling and cell-cell interactions, to the macroscopic, tissue-level scale of multicellular dynamics, and is amenable to both experimental and theoretical investigations. Collective cell migration is distinctly different from single cell migration in terms of its biological complexity and theoretical treatment.

Our interdisciplinary program focuses on four key topics of collective cell migration, ranging from the molecular to the organismal level:

  1. Cellular mechanisms of collective movement and metastasis
  2. Mechanobiology of morphogenesis
  3. Biophysical and mathematical modelling of collective movement and morphogenesis
  4. In vivo imaging of migration and metastasis

This allows us to bring together a diverse and dynamic range of speakers, spanning the cell biology, developmental biology, physics, mathematics, and in vivo imaging fields. We believe that this multidisciplinary approach will not only facilitate interactions between alternate approaches and viewpoints but will engender an atmosphere of thinking outside one’s discipline. This Workshop aims to bring together these complementary fields to reach a common consensus on the challenges in our understanding of how cells collectively move, and how this collective migration contributes to metastasis.

About Wiston House

Wiston House

The Workshop will be held at the beautiful Wiston House, which is a 16th century Grade I listed building located at the foot of the South Downs in West Sussex. The house is surrounded by over 6,000 acres of parkland with magnificent views from the mile-long drive.

Wiston House is the home of Wilton Park, one of the world’s leading centres for the discussion of key international policy issues. Wilton Park was created in 1946 to help re-establish peace and democracy in Europe as part of an initiative inspired by Winston Churchill. Wiston House has an amazing history and appears in the Domesday Book, the register of English possessions made by William the Conqueror in 1086, 20 years after he won the Battle of Hastings.

Wiston House is 32 miles from Gatwick Airport and 60 miles from Heathrow Airport. The nearest train station is Shoreham-by-Sea, which is a 20 minute taxi ride from Wiston House and takes 1 hour 10 minutes from London Victoria.

Wiston House
Steyning Road
West Sussex
BN44 3DZ
Tel: +44 (0) 1903 815020

Apply here

If you are an early-career researcher you can apply to attend the Workshop here. The deadline for applications is 19 August 2022.

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The Company of Biologists is widely known for its excellence in scientific publishing and it now runs a successful high level series of Workshops. The Workshops provide leading experts and early career scientists from a diverse range of scientific backgrounds with a stimulating environment for the cross fertilisation of interdisciplinary ideas. The programmes are carefully developed and are intended to champion the novel techniques and innovations that will underpin important scientific advances.


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